Set during the fall of Rapture, players assume the role of a Plasmid test subject for Sinclair Solutions, a premier provider of Plasmids and Tonics in the underwater city of Rapture that was first explored in the original BioShock.

Experience seamless transitions between real-time gameplay and in-game cinematics. Do you have the courage to face your destiny? Embark on a journey through the worlds of Cocoon and Pulse, encountering and fighting alongside a diverse group of allies.

Once again stepping into the role of the heroic Commander Shepard, gamers command their crew on a suicide mission in space. Players must assemble their squad from amongst the galaxy's most powerful mystics, geniuses, and convicts.